Established 2026 · Free Educational Resources for All

Biology · 100-Mark Comprehensive Assessment

Biology Comprehensive Practice Test 5

A 100-mark Biology assessment covering 0-0-9 — Reproduction, Growth & Development, 0-0-10 — Photosynthesis, Plant Nutrition & Transport — progressing from foundational knowledge to application, analysis and higher-order reasoning.

EDUSAMBAM Editorial Team·45 questions · 100 marks·Basic → Advanced

Questions

100

Marks

Sections

100%

Auto-Graded

A — Multiple Choice	15	2	30
B — True / False	10	2	20
C — Fill in the Blank	10	2	20
D — Column Matching	5 pairs	2	10
E — Short Answer	5	4	20
Total	45	—	100
Total	45	—	100

Fill-in-the-blank and short-answer questions are checked automatically against accepted answers — exact wording does not need to match, but the key term should be present.

0 of 45 answered

0/100

You scored 0%

Keep practicing

Section A — Multiple Choice

30 marks

15 questions · 2 marks each.

1.The nucleus of a eukaryotic cell contains:Basic2 pts

A. Chromosomal DNA

B. Only ATP

C. Only lipids

D. Cell wall material

2.A chromosome is best described as:Basic2 pts

A. DNA associated with proteins and organised into a structural unit

B. A type of carbohydrate

C. A membrane-bound organelle without DNA

D. A single protein

3.A gene is best understood as:Basic2 pts

A. A functional DNA sequence or region contributing to a biological product or regulatory function

B. An entire organism

C. A cell organelle

D. A lipid droplet

4.DNA replication is described as semiconservative because:Basic2 pts

A. Each daughter DNA molecule contains one parental strand and one newly synthesised strand

B. Both strands are entirely new

C. No parental DNA is retained

D. Only proteins are copied

5.Meiosis is important in sexual reproduction because it:Basic2 pts

A. Produces haploid cells and contributes to genetic variation

B. Produces identical diploid body cells only

C. Stops chromosome segregation

D. Eliminates all variation

6.A mutation is:Intermediate2 pts

A. A change in genetic material sequence or structure

B. Always harmful

C. Always beneficial

D. Always caused by exercise

7.During gene expression, DNA information can be used to produce:Intermediate2 pts

A. RNA and, for protein-coding genes, proteins

B. Only lipids

C. Only carbohydrates

D. Only ATP

8.Crossing over during meiosis can:Intermediate2 pts

A. Exchange DNA between homologous chromosomes and increase variation

B. Double chromosome number in every gamete

C. Stop DNA replication permanently

D. Create a new organ

9.If two heterozygous parents have a recessive allele for a trait, a child can inherit:Intermediate2 pts

A. Two recessive alleles

B. Only dominant alleles

C. No alleles

D. Four chromosomes from each parent

10.A phenotype is influenced by:Intermediate2 pts

A. Genotype and environment, depending on the trait

B. Genes only in every case

C. Environment only in every case

D. Chromosome number only

11.A mutation in a non-coding regulatory region can matter because:Advanced2 pts

A. It may alter when, where or how strongly a gene is expressed

B. Non-coding DNA can never have function

C. It automatically creates a new species

D. It always changes the amino-acid sequence

12.Genetic variation is important to evolution because:Advanced2 pts

A. It provides differences on which evolutionary processes can act

B. It prevents inheritance

C. It makes all individuals identical

D. It stops natural selection

13.A karyotype is useful for examining:Advanced2 pts

A. Chromosome number and large-scale chromosome structure

B. Only blood glucose

C. Only enzyme activity

D. Only species behaviour

14.If a cell fails to separate chromosomes correctly during meiosis, the gametes may:Advanced2 pts

A. Receive abnormal chromosome numbers

B. Become bacteria

C. Lose all DNA

D. Become identical to the parent

15.Which statement best integrates heredity?Advanced2 pts

A. DNA is organised into chromosomes; genes are expressed through regulated processes; meiosis and fertilisation transmit and reshuffle genetic information

B. Genes act independently of cells

C. Chromosomes are made only of RNA

D. Environment has no role in phenotype

Section B — True / False

20 marks

10 questions · 2 marks each.

16.DNA contains information encoded in the sequence of its nucleotides.Basic2 pts

True

False

17.Every mutation causes a visible disease.Basic2 pts

True

False

18.Somatic cells and gametes normally have different chromosome-number states in organisms with sexual reproduction.Basic2 pts

True

False

19.Meiosis normally produces genetically identical daughter cells.Basic2 pts

True

False

20.Gene expression can be regulated.Basic2 pts

True

False

21.A dominant allele is always more common in a population than a recessive allele.Intermediate2 pts

True

False

22.Crossing over occurs between homologous chromosomes during meiosis.Intermediate2 pts

True

False

23.Mutations can be neutral, harmful or beneficial depending on context.Advanced2 pts

True

False

24.A person's genotype and phenotype are always identical concepts.Advanced2 pts

True

False

25.Genetic information can influence traits without being the only influence on every trait.Advanced2 pts

True

False

Section C — Fill in the Blank

20 marks

10 questions · 2 marks each. Type the missing word or term.

26.The hereditary molecule DNA is organised into structures called ______.Intermediate2 pts

27.A functional region of DNA is commonly called a ______.Intermediate2 pts

28.DNA copying before cell division is called DNA ______.Intermediate2 pts

29.The division process that produces haploid gametes is ______.Intermediate2 pts

30.The physical appearance or measurable characteristics of an organism form its ______.Intermediate2 pts

31.The genetic constitution of an organism is its ______.Advanced2 pts

32.A change in DNA sequence is a ______.Advanced2 pts

33.The process by which information in a gene is used to make a functional product is gene ______.Advanced2 pts

34.Exchange of DNA between homologous chromosomes is called ______ over.Advanced2 pts

35.A cell containing two sets of homologous chromosomes is described as ______.Advanced2 pts

Section D — Column Matching

10 marks

Use the ▲ ▼ buttons to reorder Column B until each row lines up with the correct term in Column A. 2 marks per correct pair.

36–40.Match each term in Column A with the correct description in Column B.Advanced10 pts

Column A

DNA

Gene

Chromosome

Meiosis

Mutation

Column B

B. Functional DNA region

C. Organised DNA-protein structure

D. Produces haploid cells and reshuffles variation

E. Change in genetic material

A. Stores hereditary information

Section E — Short Answer

20 marks

5 questions · 4 marks each. Answer in one or two sentences.

41.Explain the relationship among DNA, genes and chromosomes.Advanced4 pts

42.Why is meiosis important for both chromosome-number stability and genetic variation in sexual reproduction?Advanced4 pts

43.Explain why a mutation is not automatically harmful.Advanced4 pts

44.How can two people with similar genes show different phenotypes?Advanced4 pts

45.A child has a recessive condition while both parents are unaffected. Explain a plausible inheritance pattern.Advanced4 pts

← Gateway